| Tenure
| Incumbent
| Affliation
| Notes
|
| Upper Oubangui (Oubangui-Chari) French overseas territory
|
| 14 May 1957 to 8 December 1958 | Abel Goumba, Vice President of the Government Council | |
|
| 26 July 1958 to 1 December 1958 | Abel Goumba, President of the Government Council | |
|
| Central African Republic | Autonomous
|
| 8 December 1958 to 29 March 1959 | Barthélémy Boganda, Prime Minister | MESAN |
|
| 30 March 1959 to 30 April 1959 | Abel Goumba, acting Prime Minister | MESAN | 1st Term
|
| 1 May 1959 to 13 August 1960 | David Dacko | MESAN |
|
| Central African Republic | Independence from France
|
| (République Centrafricaine)
|
| 13 August 1960 to 14 August 1960 | David Dacko | MESAN | (contd.)
|
| 3 January 1975 to 7 April 1976 | Elisabeth Domitien, Prime Minister | MESAN | ♀
|
| Central African Empire
|
| 4 December 1976 to 8 December 1976 | | |
|
| 8 December 1976 to 14 July 1978 | Ange-Félix Patassé, Prime Minister | MESAN |
|
| 14 July 1978 to 20 September 1979 | Henri Maïdou , Prime Minister | MESAN |
|
| Central African Republic
|
| (République Centrafricaine) (Ködrö tî Bê-Afrîka)
|
| 20 September 1979 to 26 September 1979 | Henri Maïdou , Prime Minister | MESAN |
|
| 26 September 1979 to 22 August 1980 | Bernard Ayandho , Prime Minister | MESAN/UDC |
|
| 12 November 1980 to 4 April 1981 | Jean-Pierre Lebouder , Prime Minister | UDC |
|
| 4 April 1981 to 1 September 1981 | Simon Narcisse Bozanga , Prime Minister | UDC |
|
| 15 March 1991 to 4 December 1992 | Edouard Frank , Prime Minister | RDC |
|
| 4 December 1992 to 26 February 1993 | Timothée Malendoma , Prime Minister | FC |
|
| 26 February 1993 to 25 October 1993 | Enoch Derant Lakoué , Prime Minister | PSD |
|
| 25 October 1993 to 12 April 1995 | Jean-Luc Mandaba , Prime Minister | MLPC |
|
| 12 April 1995 to 6 June 1996 | Gabriel Koyambounou , Prime Minister | MLPC |
|
| 6 June 1996 to 30 January 1997 | Jean-Paul Ngoupande, Prime Minister | PUN |
|
| 30 January 1997 to 1 February 1999 | Michel Gbezera-Bria, Prime Minister | n-p |
|
| 1 February 1999 to 1 April 2001 | Anicet Georges Dologuélé , Prime Minister | MLPC |
|
| 1 April 2001 to 15 March 2003 | Martin Ziguélé, Prime Minister | MLPC |
|
| 23 March 2003 to 12 December 2003 | Abel Goumba, Prime Minister | FPO | 2nd Term
|
| 12 December 2003 to present | Célestin Le Roi Gaombalet , Prime Minister | n-p |
|
